RNAProtein160-page4 - 3 Transfer RNA(tRNA • There are a...

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Gene Expression – DNA to Protein - 4 2 . Ribosomal RNA (rRNA) Ribosomal RNA is a component, with protein, of the ribosomes. A ribosome is composed of 2 subunits, a small subunit containing RNA molecules plus proteins, and a larger subunit containing RNA plus proteins and the enzymes needed for protein synthesis. The ribosomal subunits are manufactured in the nucleolus, but the complete ribosome is found in the cytoplasm, frequently attached to rough endoplasmic reticulum. The small rRNA subunit has a binding site for mRNA molecules during protein synthesis. The larger subunit has three attachment sites for tRNA molecules, the P site, A site and E site (Exit site). During protein synthesis the two subunits bind together.
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Unformatted text preview: 3 . Transfer RNA (tRNA) • There are a variety of tRNA molecules in the cytoplasm of the cell. • Each tRNA has hairpin loops in which the RNA is folded back on itself making hydrogen bonds. • Each different type of tRNA has two important pieces: 1. An amino acid attachment site at the 3' end, which can attach to one specific amino acid 2. A special tRNA triplet sequence, which pairs with one specific mRNA triplet sequence. This triplet specifies the precise amino acid that attaches to the attachment site of the tRNA. • tRNA is the critical connection between the information carried on the DNA and the amino acids that will be assembled into proteins...
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