RNAProtein160-page10 - Selective intron splicing in sex...

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Gene Expression – DNA to Protein - 10 Why Introns? Why does so much of the DNA molecule contain introns? Some reasons might be: One pre-mRNA can be used to code for more than one protein, depending on what is determined to be introns in the processing stage. The same DNA can code for different molecules in different organs depending on the splicing. One might produce a hormone and one a chemical messenger. The proteins that determine gender development in fruit flies have been shown to share a common pre-mRNA.
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Unformatted text preview: Selective intron splicing in sex determination in fruit flies • Introns may help in modifying protein shape. Different introns can affect the location of an active site for an enzyme or the attachment site for a membrane protein. This may affect change in proteins through time, and result in new, different proteins. • It is also believed that length of introns affects rate of recombination, a process that occurs during meiosis and results in more genetic variation....
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