Gene Expression – DNA to Protein - 17 Translocation Red and Green illuminated chromosomes illustrate translocation. Impacts of Chromosome Mutations The impacts of chromosomal mutations vary depending on when and where the mutation occurs. In some cases, the cell will not work, and dies. In gametes, they will be carried in all cell lines, and there is some evidence that some chromosomal alterations may activate oncogenes, or cancer causing genes. One form of leukemia is caused by a translocation between chromosomes 9 and 22. Point Mutations In contrast to chromosome mutations that involve entire genes or regions of chromosomes, point mutations are changes that affect one or just a few nucleotides. Point mutation impacts are readily seen in protein synthesis, and we will revisit some of the impacts of mutation on protein synthesis in that section. . Deletions, Insertions, inversions and translocations can all occur as point mutations as well as chromosomal mutations. Types of Point Mutations
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This note was uploaded on 12/29/2011 for the course BIO 151 taught by Professor Edwards during the Spring '10 term at SUNY Stony Brook.