BASAL CELL CARCINOMA

BASAL CELL CARCINOMA - 1. BASAL CELL CARCINOMA The most...

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1. BASAL CELL CARCINOMA The most common cancer affecting humans Slow growing At least 75% first tumours are on the face Relatively ‘benign’ in most cases – but if left untreated can be disfiguring and life threatening
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AETIOLOGY AND EPIDEMIOLOGY The most important risk factor is solar ultraviolet radiation Type 1 skin Episodes of painful sunburn in early life Mechanism of injury by UV radiation is complex: direct DNA damage damage to repair mechanisms immune dysregulation mutations in p53 suppressor genes
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TYPES OF BCC (1) NODULAR Usually begin as a small pink ‘pearly’ papule Develop a depression in the centre Rolled edge Overlying telangiectasia
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TYPES OF BCC (2) SUPERFICIAL Usually found on the trunk May be multiple Flat red patches Usually have typical beaded edge
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TYPES OF BCC (3) MORPHOEIC White or waxy Always on face Presents as a spontaneous ‘scar’ Margins are usually much wider than what is clinically visible
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TYPES OF BCC (4) Multifocal Bowenoid – usually found on lower legs of women with sun damaged skin. Diagnosis by biopsy Poorly differentiated
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BASAL CELL CARCINOMA - 1. BASAL CELL CARCINOMA The most...

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