LecturePP25Mycobacterium

LecturePP25Mycobacterium - Mycobacterium Important Human...

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Mycobacterium
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Mycobacterium tuberculosis Mycobacterium leprae (uncommon) Mycobacterium avium-intracellulaire Complex (MAC) or (M. avium) Important Human Pathogens
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Lipid-Rich Cell Wall of Mycobacterium Mycolic acids CMN Group: Unusual cell wall lipids (mycolic acids,etc.) ( P urified P rotein D erivative)
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Acid-Fast (Kinyoun) Stain of Mycobacterium NOTE : cord growth (serpentine arrangement) of virulent strains
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Photochromogenic Mycobacterium kansasii on Middlebrook Agar NOTE : Mycobacteria pathogenic for humans can be differentiated ( Runyon Groups ) by: speed of growth (all are slower than most other pathogens) and by production of chromogenic pigments (in light, in dark, or none)
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Improved Mycobacterial Isolation Medium
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Eight Week Growth of Mycobacterium tuberculosis on Lowenstein-Jensen Agar
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Pathogenic Mycobacterium spp. BCG AIDS patients
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Mycobacterial Clinical Syndromes
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Diagram of a Granuloma NOTE: ultimately a fibrin layer develops around granuloma (fibrosis) , further “walling off” the lesion. Typical progression in pulmonary TB involves caseation , calcification and cavity formation .
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Laboratory Diagnosis of Mycobacterial Disease Nucleic acid probes Nucleic acid sequencing
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Differential Characteristics of Commonly Isolated Mycobacterium spp.
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Mycobacterium tuberculosis
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Mycobacterium tuberculosis Infections
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Incidence of Tuberculosis in USA
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