Nasal polyps - Nasal Polyps Mr Stephen OHanlon Introduction...

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Nasal Polyps Mr Stephen O’Hanlon
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Introduction Abnormal lesions that emanate from portion of nasal mucosa or paranasal sinuses Benign polyps Other benign or malignant tumours
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Nasal polyps Endoscopic view of left nasal cavity. Polyp protruding from uncinate process
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Nasal polyps Left anterior nasal cavity showing an antro-coanal polyp. Sucker is pushing inferior turbinate to one side
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Pathophysiology Unknown Chronic inflammation Autonomic nervous system dysfunction Genetic predisposition Allergic verses non-allergic
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Pathophysiology Associated with allergic conditions 20-50% have asthma Allergic rhinitis 8-26% have aspirin intolerance 50% have alcohol intolerance
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Pathophysiology Non allergic conditions Cystic Fibrosis 6-48% have polyps AFS 85% have polyps Young syndrome Churg-Strauss syndrome
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Pathophysiology Coronal CT scan of sinuses of patient with cystic fibrosis
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Pathophysiology Allergic fungal sinusitis
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Pathophysiology Polyps are more common in patients with non-allergic asthma (13%) than allergic asthma (5%) 3000 atopic patients 0.5% have polyps Norlander et al (1999)
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Pathophysiology Various theories Bernstein theory Vasomotor theory Epithelia rupture theory
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Nasal polyps - Nasal Polyps Mr Stephen OHanlon Introduction...

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