Osteoporosis - Osteoporosis New Trends in Prevention and...

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Osteoporosis New Trends in Prevention and Treatment Prof. Bari Kaplan MD . . 2-4-2003
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The management of postmenopausal osteoporosis first focuses on identifying the woman’s risk factors, then selecting measures that will reduce modifiable risk factors through lifestyle changes and, if indicated, pharmacologic therapy.
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If pharmacologic therapy is indicated FDA-approved options are: Estrogens (prevention only) according FDA new statement. Bisphosphonates and Selective estrogen- receptor modulators (prevention and treatment), Calcitonin (treatment only). PTH
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Anti fracture efficacy of the most frequently used treatment of postmenopausal osteoporosis in addition to the effects of calcium or vitamin D supplementation, or both, as derived from placebo controlled randomized trials . DRUG Vertebral # Non Vertebral # Alendronate +++ ++ Calcitonin + 0 Etidronate + 0 Fluoride ± - HRT + 0 PTH +++ ++ Raloxifene +++ 0 Risedronate +++ ++ Vitamin D derivatives ± 0 Delmas, The Lancet 359:2018-2026, 2002
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Osteoporosis - Osteoporosis New Trends in Prevention and...

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