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Unformatted text preview: APh161: Physical Biology of the Cell Homework 3 Due Date: Thursday, January 28, 2010 Their drills are bloodless battles and their battles are bloody drills. - Josephus Comments from RP to Class: This third homework pushes you to develop some facility with binding prob- lems. This kind of analysis will be crucial for much of what we do for the rest of the course, so developing familiarity with these problems is crucial. In addition, we work a little harder to understand how to think of DNA from the polymer physics perspective. 1. Free vs Total Ligands and Binding. Do problem 6.3 of PBoC. 2. Binding Problems for Distinguishable Ligands. Do problem 6.4 of PBoC. 3. Deriving the Canonical Distribution and Using it for the Prob- lem of a Dishonest Die. Read section 6.1.5 of PBoC and rederive and explain in your own way eqns. 6.47 and 6.63. Once you have read this section, do problem 6.8 of PBoC....
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- Fall '09