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Unformatted text preview: Bi1x, Spring 2009 Week 5 Prelab The Central Dogma of Biology and Hemoglobin The goal of this problem is to develop more facility with thinking about the connection between nucleic acids and proteins as embodied in the Central Dogma of Biology. In addition, one of your first exercises in bioinformatics will be to examine sequences of hemoglobin from different organisms, so this is also an opportunity to think about hemoglobin in preparation for that exercise. Nearly all of the oxygen carried by blood in animals is bound and transported by the protein hemoglobin contained in erythrocytes (red blood cells). Each tetrameric hemoglobin molecule is composed of pairs of two different subunits, alpha ( ) and beta ( ). A portion of one strand of the gene coding for the -subunit of hemoglobin is shown below: 5'-AGTAACGGCAGACTTCTCCTCAGGAGTCAGGTGCACCATCTGTTCAGG-3' A. Write down the sequence of the complementary strand in the 5 to 3 orientation. Label both the 5' and 3' ends....
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This document was uploaded on 01/03/2012.
- Fall '09