UNIT 5 - Enolates-02-aldol problems

UNIT 5 - Enolates-02-aldol problems - EtO O OEt O Br 1....

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
SC6POC – O’Malley Enolates 2 Name: __________________ Wade: pp1017-1027 (Aldol problems) © S. O’Malley 2010 1. Show what starting materials are needed to synthesize the following aldol addition and condensation products: a. OH H O b. OH O c. O OH d. O 2. Propose a mechanism for the following: a. OEt O O 1. NaH 2. O O + EtOH b. the Darzens condensation O Cl OEt O t BuOK O OEt O
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
3. Complete the following scheme:
Background image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: EtO O OEt O Br 1. NaOEt 2. 1. NaOH 2. H 3 O + , LAH TsCl pyridine NaCN 1. Me 2 CuLi 2. H 3 O + m-CPBA NaOH H 2 O H + (-H 2 O) O O + H 2 O 4. More mechanisms : a. a retro-aldol followed by a forward aldol reaction O NaOH H 2 O O b. a Robinson annulation O OMe OMe O O OH-c. the Knovenagel condnesation H O HO O OH O NH OH O...
View Full Document

This note was uploaded on 01/01/2012 for the course CHEM 101 taught by Professor Donahue during the Spring '11 term at Long Island U..

Page1 / 2

UNIT 5 - Enolates-02-aldol problems - EtO O OEt O Br 1....

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online