Lecture - The Use of Animals in Biomedical Research Animal...

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1 1 The Use of Animals in Biomedical Research, Animal Welfare, and Animal Rights Christopher S. King, D.V.M. Diplomate ACLAM The University of Georgia 2 Presentation Outline Use of animals in biomedical research Conducting research: laws, regulations, and guidelines Animal Care and Use Committees (IACUC): composition and function Animal welfare vs. animal rights: definitions and philosophies Questions and discussion 3 “Use” of Animals in the US 6.5 Billion animals used in US annually 96% are used for food 0.3% are used in biomedical research
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2 4 Food Animal Stats 6 Billion broilers 100 million beef cattle 10 million milk cows 57 million hogs 285 million turkeys 11 million sheep 5 Animal Use in Basic and Biomedical Research • 17-22 million animals are used annually • 90% are rodents, 95% purpose bred • <0.5% are dogs and cats • <0.25% are primates • Balance are hamsters, rabbits, guinea pigs, and miscellaneous species ….put into more personally meaningful numbers 6 In a life span of 75 years the average person. .. Consumes: 600 chickens 22 pigs 20 sheep 4 cows
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3 7 In a life span of 75 years the average person. .. Used in their behalf for research: 4 mice 1 rat .005 of a dog 8 More Animal Numbers In one year in the US…. • 10-29 Million animals are destroyed in pounds • 1.2 Million dogs and 5.4 Million cats road- killed • 92 Thousand dogs and cats were used in research 9 Society Benefits from Basic and Biomedical Research using Animals Virtually all major medical advances depend on animal research 65 Nobel Prizes for Medicine involved the use of animals
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4 10 Major Medical Advances of the 20th Century 1900s. ..treatment of pellegra and rickets 1920s. ..discovery of insulin 1930s. ..sulfa drugs, tetanus prevention, modern anesthesia 1940s. ..antibiotics, Rh factor, prevention of diptheria 1950s. ..prevention of polio, cancer chemotherapy, open-heart sx 11 Major Medical Advances of the 20th Century 1960s…Px of rubella, coronary bypass, antihypertensives 1970s…Px of measles, eradication of smallpox, heart transplants, oncogenes, monoclonal antibodies 1980s. ..cyclosporin, artificial heart, breast cancer developments, hepatitis B vaccine, AZT, IVF, cholesterol-lowering drugs, metastasis 1990s. ..gene therapy, xenotransplantation, artificial organs 2000s…stem cell therapy, cloning ??????
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This note was uploaded on 01/01/2012 for the course PHRM 7230 taught by Professor Tackett during the Spring '11 term at UGA.

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Lecture - The Use of Animals in Biomedical Research Animal...

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