20 - LECTURE 20 ANNOUNCEMENTS 1. HOMEWORK ASSIGNMENT NOT AS...

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Unformatted text preview: LECTURE 20 ANNOUNCEMENTS 1. HOMEWORK ASSIGNMENT NOT AS IN LG FOR THIS WEEK! INSTEAD: TEXT pp. 343-363 & 371 - 389; PROBLEMS Ch.10#7,16 & Ch.11#4,15 AND LG 32-34 2. PYMOL #6, CHYMOTRYPSIN (WILL APPEAR ON MIDTERM EXAM) 3. REMINDER: NO QUIZ NEXT WED 10/19 LECTURE OF FRIDAY 10/7 4. MEET FRI 10/14 2:55PM COMSTOCK B108. HOW TO STUDY FOR THIS COURSE . NO DISCUSSION OF MATERIAL ON MIDTERM EXAM (THAT DISCUSSION MONDAY, IN CLASS); DISCUSSION WILL BE POSTED AS AN ADDENDUM TO FRIDAY LECTURE . TODAY 1. ALLOSTERIC REGULATION OF AN ENZYME: ASPARTATE CARBAMOYL TRANSFERASE, ENZYME THAT CAN DO R T 2. COVALENT REGULATION OF AN ENZYME: CHYMOTRYPSINOGEN CHYMOTRYPSIN LIPIDS PROPERTIES AND CHEMICAL RXNS 5. MIDTERM ROOMS ROCKEFELLER : A - M IN SCHWARTZ AUD.; N - Z IN 203 (AUD. B) 3. GENERAL MEMBRANE PROPERTIES; TYPES OF LIPID BILAYER PHASES PROTEINS IN BIOMEMBRANES FUSION OF MEMBRANES BIOMEMBRANES: GENERAL PROPERTIES ANCIENT AS THE FIRST CELL! ALWAYS COVALENTLY ATTACHED TO PROTEIN OR LIPID WHAT IS A LIPID ? WATER-INSOLUBLE, OIL-LIKE BIOMOLECULE IN BIOMEMBRANES, LIPIDS ARE AMPHI PHILIC BOTH LOVE i.e. BIOMEMBRANE LIPIDS HAVE A POLAR PART AND A NONPOLAR PART THE NONPOLAR PART GETS OUT OF WATER BIOMEMBRANE PERMEABLE TO IONS, SUGARS, AA, PROTEINS, NUCLEOTIDES NOT PERMEABLE TO NOTICE ASYMMETRY ASYMMETRY OF LIPIDS HARD TO STUDY H 2 O, O 2 , N 2 , CO 2 , EtO STEROLS, DIFF. LIPIDS, DIFF. PROTEINS IN THE OUTER LEAFLET, COMPARED WITH THE INNER LEAFLET: Nucleus Cytosol 30-70% PROTEIN 30-70% LIPID ~5% CARBO COMPOSITION BY MASS: USED HERE AS JARGON 3 KEY TYPES OF LIPID BILAYER PHASES 1. LIQUID 3. LIQUID- ORDERED ACYL CHAINS STRAIGHT , BUT PROTEINS & LIPIDS MOVE ; MUCH OF PLASMA MEMBRANE LIKE THIS. IT IS...
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20 - LECTURE 20 ANNOUNCEMENTS 1. HOMEWORK ASSIGNMENT NOT AS...

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