21 - Friday, October 14, 2011 Lecture 21 Announcements: 1....

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Friday, October 14, 2011 Lecture 21 Announcements: 1. Make-up exam for midterm: Sunday 10/23, 1 - 3:30PM. In order to take this exam, you must be on prof’s list (exam conflict; 3 exams in 24hr), or be sick on 10/20 (and please do let prof know about that, too, if you can). 2. Note that the midterm exam will be comprehensive, up to and including LG p. 158. 3. Meet today at 2:55PM in Comstock B108 to discuss “How to study for this course”. There will be no discussion of what material will be on the exam (that discussion will take place in class Monday 10/17 at the end of lecture). This Friday discussion will be posted as an addendum to this lecture. 4. The final exam will be on Monday 12/12/11, 2 - 4:30PM , in Call Auditorium in Kennedy Hall. There will be a make-up final exam, but that date must be AFTER 12/12 in order to accommodate any students who are sick on 12/12. Sorry for any inconvenience, but please do not contact the prof to ask for a special early final exam . 5. Reminder: pick up any quizzes that you did not get in class at the Reserve Desk of the Biology Center, 2 nd floor of Stimson Hall. 6. Review sessions for the midterm exam: The Monday evening session will be dedicated to the lectures and problem assignments associated with LG pages up to 106; the Tuesday afternoon review session will be dedicated to the material in the LG from pp. 107 – 158. Wednesday's lecture: . general properties of a biological membrane . types of fatty acyl chains found in membranes . structure of 2-chain lipids . action of phospholipases . proteins anchored in membranes . fusion of membranes Today's lecture: Now we have all the tools of enzymology, and the basics of biomembrane function, for understanding control of metabolism. Soon, we will be starting the discussion of energy metabolism with the carbohydrate glucose. So first, let’s discuss carbohydrates, p. 159.
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Goals of this discussion of carbohydrates: . Carbohydrate terminology . Carbohydrate structure . Carbohydrate types . Carbohydrate roles See the text pages 235-244 and learn the nomenclature, stereochemistry and conventions. You must learn this without lecture assistance. The lectures will focus on interesting chemistry and structures. A main point in looking at carbohydrate structures is to see the great variety of small differences in the structures. A beginning biochemistry student studies these tiny variations and thinks, "so what?". But an enzyme can recognize even the tiniest such variation and bind it selectively. The huge variety of structures of carbohydrates makes this class of biomolecules different from proteins, nucleic acids, and lipids. Each type of biomolecule has its own "rules" and special properties, and variety is one of the keys for carbohydrates. At the top of page 159 is D-Ribose in Fischer projection form.
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21 - Friday, October 14, 2011 Lecture 21 Announcements: 1....

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