31 - LECTURE 31 ANNOUNCEMENTS 1 PROBLEM ASSIGNMENTS AS IN LG AND PyMOL#9 ATP SYNTHASE FRIDAY'S LECTURE • COMPLETE OX OF ACETYL GROUP ∴

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Unformatted text preview: LECTURE 31 ANNOUNCEMENTS 1. PROBLEM ASSIGNMENTS AS IN LG; AND PyMOL #9, ATP SYNTHASE FRIDAY'S LECTURE • COMPLETE OX OF ACETYL GROUP ( ∴ COMPLETING THE OX OF GLUCOSE) • • CONTROL AT THE 3 STEPS WHERE ENZYMES NOT FULLY ACTIVE-- RECOGNIZE BY LARGE NEGATIVE ∆ G OF THE RXN. PDH COMPLEX RXN RATE ALSO UNDER CONTROL. • CAC INTERMEDIATES ARE DIRECTLY CONNECTED TO AA BIOSYN, FATTY ACID AND STEROID BIOSYN, PORPHYRIN BIOSYN, SYN OF NUCLEOTIDE PURINES & PYRIMIDINES. RXNS OF THE CITRIC ACID CYCLE : • FATTY ACID UPTAKE FROM DIET: NO CONTROL! TODAY • FATTY ACID CATABOLISM BY β-OXIDATION; "KETONE BODIES" • AMINO ACID CATABOLISM: WHAT HAPPENS TO THE AA, AND TO THE AMMONIA ! 2. LET'S SET A DAY & TIME FOR THE MAKE-UP FINAL. CHECK YOUR EXAM WEEK SCHEDULE. IF YOU HAVE A CONFLICT, MEET BRIEFLY AFTER CLASS WED 11/9 • FA RELEASE FROM STORED FAT: HORMONAL CONTROL • FA “ACTIVATION” FOR TRANSPORT INTO MITO MATRIX • FA TRANSPORT ACROSS INNER MITO MEMBRANE 3. TUESDAY 11/8: CURB PRESENTS A FALL RESEARCH FORUM PALMITOYL CARNITINE ONCE FA IS INSIDE CELL, FOR ENTIRE PROCESS OF FA CATABOLISM: TRANSPORTING FA INTO MITO MATRIX IS THE REGULATED STEP! HOW FA IN CYTOSOL GETS INTO THE MITOCHONDRIAL MATRIX, CONT'D CARNITINE PRESERVES HIGH-ENERGY LINKAGE KEY METABOLITES e.g. CoA ARE PREVENTED FROM CONCENTRATING IN ANY COMPARTMENT OF THE CELL BECAUSE--...
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This note was uploaded on 01/01/2012 for the course BIOMG 3310 taught by Professor Feigenson during the Fall '11 term at Cornell University (Engineering School).

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31 - LECTURE 31 ANNOUNCEMENTS 1 PROBLEM ASSIGNMENTS AS IN LG AND PyMOL#9 ATP SYNTHASE FRIDAY'S LECTURE • COMPLETE OX OF ACETYL GROUP ∴

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