Week 7 C Chapter 36 Early Effects of Radiation Exposure

Week 7 C Chapter 36 Early Effects of Radiation Exposure -...

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Chapter 36 Early Effects of Radiation In the 1920’s & 1930’s if was not uncommon for radiologic technologist to get hematologic exams weekly. Blood work was used to monitor the worker for over exposure before dosimeters were available. In the 1960’s blood work was done quarterly and dosimeters were worn.
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Early Effects of Radiation In humans, a response to radiation that occurs within months of the exposure is called Early Effects. Death is the most devastating human response to radiation. No deaths immediately after diagnostic radiography have ever been reported.
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Early Effects of Radiation Many of the pioneers in radiology died from long term effects of exposure. Diagnostic x-ray beams always result in partial body exposure, which is much less effective at producing a response than whole body exposure.
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Major Lethal Exposures in Humans 1945 Atomic Bombs in WW2 1979 Three Mile Island Nuclear Power Plant Accident killed one person. 1986 Chernobyl Russia nuclear reactor melt down killed 30 people (official) 500,000 reported. Military accidents have also killed humans.
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Early Effects Death Whole Body 200 rad/ 2Gy T Hematolic Depression Whole Body 25 rad/ 0.25 Gy T Skin Erythema Small Field 200 rad/ 2Gy T Epilation Small Field 300 rad/ 3Gy T
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Early Effects Chromosome aberration Whole Body 5 rad Gonadal Dysfunction Local Tissue 10 rad
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Acute Radiation Syndrome 1. Prodormal period: acute symptoms within hours of exposure. 2. Latent period: time free of any visible effects. 3. Manifest illness: Hematologic syndrome Gastrointestinal syndrome Central Nervous System Syndrome 4. Recovery or Death
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Prodromal Period Prodromal period may last for a few hours or a couple of days. Symptoms include nausea, vomiting and diarrhea. Severity of symptoms are dose related. For extremely high exposure it is hard to distinguish Prodromal from manifest illness
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Latent Period After prodormal radiation sickness there is a period of apparent well-being called the Latent Period. With very high exposure, it may last only a few hours. For lower exposures, it may last for weeks. May be mistakenly thought to be recovery from moderate exposure.
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Latent Period Biologic and physiologic changes are occurring even though they give no indication of the response yet to follow. Responses are extremely variable relative to dose. High exposure will skip the latent period while low exposure may not have the Prodromal period.
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Manifest Illness Manifest Illness is a dose related period characterized by three separate syndromes. Hematologic Syndrome Gastrointestinal Syndrome Central Nervous System Syndrome
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The hematologic syndrome is produced with exposures of 200 to 1000 rads. The prodormal period will be rather mild
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This note was uploaded on 01/03/2012 for the course LC 232 taught by Professor Wilson during the Fall '08 term at Palmer Chiropractic.

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Week 7 C Chapter 36 Early Effects of Radiation Exposure -...

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