21b Rs Regulation

21b Rs Regulation - REGULATION OF RESPIRATION Page 1...

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REGULATION OF RESPIRATION AC Brown Page 1 A7c NEUROGENESIS OF RESPIRATION A. Introduction 1. Neurogenesis define: function of CNS structures responsible for establishing the basic respiratory rhythm 2. Terms: apnea no ventilation hyperpnea high frequency of ventilation hypoventilation insufficient ventilation for metabolic needs; indicated by P A-CO2 > 42 mmHg hyperventilation excess ventilation in relation to metabolic needs; indicated by P A-CO2 < 38 mmHg dyspnea subjective sensation of difficulty in breathing; generally indicates the physiological demand for ventilation exceeds the person’s ability to respond
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REGULATION OF RESPIRATION AC Brown Page 2 A7c NEUROGENESIS OF RESPIRATION A. Introduction (continued) 3. Two neurogenic systems (both CNS) a. involuntary (automatic): involve medulla, pons, limbic system (emotional responses), hypothalamus (temperature regulation), and other subcortical structures b. voluntary : involve cerebral cortex Note 1: systems independent Note 2: both systems require intact innervation of respiratory muscles (alpha motoneurons) Note 3: the muscles of respiratory ventilation are controlled by the somatic motor system, not the autonomic system (the autonomic system controls airway smooth muscle contraction and secretion) B. Medulla (Respiratory Center) 1. anatomy: two groups of cells a. inspiratory (I) neurons; control muscles of inspiration b. expiratory (E) neurons; control muscles of expiration 2. necessary for respiration: destruction leads to immediate and permanent cessation of automatic respiration 3. sufficient for respiration: even when isolated from other neural
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This note was uploaded on 01/03/2012 for the course BIO 308 taught by Professor Acbrown during the Spring '10 term at Portland.

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21b Rs Regulation - REGULATION OF RESPIRATION Page 1...

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