StudyGuide-1-11

StudyGuide-1-11 - BIO 308: Study Guide Spring Semester 2007...

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BIO 308: Study Guide Spring Semester 2007 AC Brown page 1 MEMBRANE TRANSPORT through AUDITORY SYSTEM A7b Objectives: The student shall know the facts, understand the concepts, and be able to deduce the consequences for each of the following: MEMBRANE TRANSPORT & MEMBRANE POTENTIAL Distribution of Na+, K+, Cl-, glucose, and protein in interstitial and intracellular fluids Sign and magnitude of the resting potential in mammalian nerve and skeletal muscle cells Factors determining transport rate across biological membranes Definitions of permeability and net driving force Mechanism, permeability, selectivity, characteristics and roles of each of the following modes of membrane transport: Dissolve in the lipid bilayer Simple diffusion through membrane channels Facilitated diffusion; uniport, symport, antiport Active transport (primary & secondary); application to the resting neuron membrane and intestinal absorption of sodium, glucose, and water Water transport; definitions of solution osmolarity and tonicity Vesicular transport; endocytosis and exocytosis Components of electrochemical (passive) driving force for membrane movement Factors that determine the ion distribution and resting membrane potential of neurons and the relative contribution of each EXCITABILITY & ACTION POTENTIALS Components of neurons and their function(s) Definitions of nerves, tracts, ganglia, and nuclei Response of excitable tissue to depolarizing stimuli Action Potential characteristics: shape and timing, threshold, all-or-none, refractory period, ion movements Ion channels associated with the action potential and how their properties determine the action potential characteristics Ionic basis of the action potential shape, threshold, and refractory period Role of active transport in excitable tissue Action potential (AP) propagation (conduction) in unmyelinated and myelinated axons; saltatory conduction Speed of AP conduction and factors determining its value Alterations in action potential propagation: action of local anesthetics, effect interstitial K+ concentration, effect of demylination diseases
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BIO 308: Study Guide Spring Semester 2007
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StudyGuide-1-11 - BIO 308: Study Guide Spring Semester 2007...

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