chapter15b Blood Flow and the Control of Blood Pressure 2

chapter15b Blood Flow and the Control of Blood Pressure 2 -...

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Chapter 15b Blood Flow and the Control of Blood Pressure
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Arteriolar Resistance Arteriolar resistance is influenced by both local and systemic control mechanisms Local control Sympathetic reflexes Hormones
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Arteriolar Resistance Table 15-2
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Arteriolar Resistance Myogenic autoregulation Paracrines Active hyperemia Reactive hyperemia Sympathetic control SNS: norepinephrine Adrenal medulla: epinephrine
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Hyperemia is a Locally Mediated Increase in Blood Flow Figure 15-11a
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Hyperemia is a Locally Mediated Increase in Blood Flow Figure 15-11b
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Norepinephrine Tonic control of arteriolar diameter Figure 15-12
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Distribution of Blood Distribution of blood in the body at rest Figure 15-14
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Blood Flow Blood flow through individual blood vessels is determined by vessel’s resistance to flow Figure 15-15a
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Blood Flow Flow  1/resistance Figure 15-15b
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Precapillary Sphincters Figure 15-16a
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Precapillary Sphincters Figure 15-16b
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Capillaries: Exchange Plasma and cells exchange materials across thin capillary wall Capillary density is related to metabolic activity of cells Capillaries have the thinnest walls Single layer of flattened endothelial cells Supported by basal lamina Bone marrow, liver and spleen do not have typical capillaries but sinusoids
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Two Types of Capillaries Figure 15-17a Basement membrane Endothelial cell junctions Transcytosis vesicles Endothelial cells Nucleus (a) Continuous capillaries have leaky junctions.
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Two Types of Capillaries Basement membrane (cut) Basement membrane Endothelial cell junction junction Transcytosis vesicles Fenestrated pores (b) Fenestrated capillaries have large pores. Fenestrations or pores Figure 15-17b
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Velocity of Blood Flow Velocity of flow depends on total cross-sectional area of the vessels Figure 15-18
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Capillary Exchange Exchange between plasma and interstitial fluid occurs by paracellular pathway or endothelial transport Small dissolved solutes and gasses move by diffusion Larger solutes and proteins move by vesicular transport In most capillaries, large proteins are transported by transcytosis
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Capillary Exchange Bulk flow Mass movement as a result of hydrostatic or
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This note was uploaded on 01/03/2012 for the course BIO 308 taught by Professor Acbrown during the Spring '10 term at Portland.

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chapter15b Blood Flow and the Control of Blood Pressure 2 -...

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