18 cardiovasc2007medfinal_nxpowerlite_

18 cardiovasc2007medfinal_nxpowerlite_ - Circulatory System...

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Circulatory System MCTB Ross, Chapter 13 Dr. Kelly Selman September 28, 2007 Cardiovascular System
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Heart: a muscular pump that maintains a unidirectional flow of blood Endocardium Myocardium Epicardium Visceral pericardium Endothelium and subendothelial CT Middle layer of CT and smooth muscle Subendocardial layer: CT layer with Purkinje fibers (PF) PF are specialized cardiac muscle cells that are part of the impulse conducting system and extend from AV node Cardiac muscle that is connected to a fibrous CT skeleton Atria have smaller cells and fewer T- tubules; thinner muscle layer in atria than ventricles ANF: atrial natriuretic factor (peptide hormone) Low-friction surface, that faces the pericardial cavity. Consists of mesothelium and underlying CT Has coronary BV, nerves, adipose tissue (cushioning)
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Myocardium Endocardium Purkinje fibers
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Purkinje fibers 41.9um 31.2um 17.1um Bundles of impulse special conducting cardiac muscle cells Generate & conduct electrical impulses throughout heart Extend from A-V node and line interventricular septum Aid in coordinating contraction of ventricles Large, fewer myofibrils, much glycogen
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Atrial natriuretic factor (ANF) (natrium=sodium) Atrial cardiac muscle cells are stimulated (by stretching or high sodium intake) to synthesize atrial natriuretic factor (ANF), and secrete it as a prohormone that is enzymatically cleaved and circulates in the blood. Functions as a diuretic. By increasing the filtration rate in the kidney, it increases excretion of Na + and thus more H 2 0 excreted in urine . Relaxes smooth muscle (helps control blood pressure) Blood vessel Atrial cell granules ID
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Pericardial cavity Mesothelium Adipocytes Coronary BVs Epicardium (Visceral pericardium)
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Elastic arteries Arterioles Capillaries Venules Veins Muscular arteries Systemic and Pulmonary Circulation
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What does the Cardiovascular System have to do? Maintain blood flow to all organs in the body Adjust the flow to organs as their needs change Provide enough flow and pressure for capillary exchange to occur Have enough blood pressure after capillary beds for blood to return to the heart Structure and function are highly correlated
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Structural organization of heart and blood vessels Heart: endocardium myocardium epicardium BVs: tunica intima tunica media tunica adventitia Structure of blood vessel wall Blood vessels are structurally
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This note was uploaded on 01/04/2012 for the course ANT 610C taught by Professor Johnaris during the Spring '10 term at University of Florida.

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18 cardiovasc2007medfinal_nxpowerlite_ - Circulatory System...

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