22 lymphatic1_lecture07print_nxpowerlite_

22 lymphatic1_lecture07print_nxpowerlite_ - Lymphatic...

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Lymphatic System I or Chasing Milkmaids Through the Woods Dr. T. G. Hollinger Medical Cell and Tissue Biology ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Lymphatic System Functional divisions of lymphatic system Anatomic divisions of lymphatic system Cells of the lymphatic system Types of Immunity ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Functional Divisions of the Lymphatic System Humoral Antibodies secreted into tissues and fluids that circulate through the vascular system (Secreted from B cells) Cellular Mediated by Cell to Cell contact (Cytolytic T lymphocytes {CTLs}, or Killer T lymphocytes) ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Anatomical Divisions Lymphatic ‘Organs’ Primary organs Bone marrow B cells mature here (*BALT?, *GALT?) Thymus T cells mature here Secondary organs Lymph nodes Spleen Tonsils Lymphatic nodules (GALT, BALT, MALT) *Lymphatic nodules are not organs in the strict sense of the word, but they function in the same manner ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Lymphatic Cells Lymphocytes B cells Memory B cells Plasma cells T cells Memory T cells Helper T cells (Th) Cytolytic T cells (Cytotoxic, killer, CTL) NK cells Accessory Cells Macrophages Dendritic cells Langerhans (skin) or follicular dendritic cell (lymph node) ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Lymphoid Cells ©Copyright, Thomas G. Hollinger, Gainesville FL 2007 Ross 5 th , p265
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What is Immunity? Think of P Immunity is the reaction of cells and tissues to foreign (nonself) p athogens P rokaryotes (microorganisms) P arasites P roteins P olysaccharides ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Types of Immunity Innate Epithelial barriers Phagocytic cells (neutrophils, macrophages) Natural killer (NK) cells Blood proteins (cytokines and complement) Acquired (Adaptive) ( is Specific, Diverse, Remembered, Self limited, Tolerant) Humoral (antibodies to antigens) B cells and plasma cells Cell-mediated T cells, B cells, and antigen presenting cells (APC) ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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Antibody molecule Ross 5 th , p 400 ©Copyright, Thomas G. Hollinger, Gainesville FL 2007
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This note was uploaded on 01/04/2012 for the course ANT 610C taught by Professor Johnaris during the Spring '10 term at University of Florida.

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22 lymphatic1_lecture07print_nxpowerlite_ - Lymphatic...

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