324Lecture7 CT - Connective Tissue Part Dos Developmental...

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Connective Tissue Part Dos
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Developmental CT-1) Mesenchyme - embryonic CT; generally confined to the first two months of embryogenesis (human). Mesenchyme cells are like fibroblasts, star shaped; much ground substance with reticular fibers that are not visible
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Developmental CT-2) Mucoid - embryonic CT (looks like mesenchyme with much matrix) occurs in late embryo and adult; limited in distribution (umbilical cord); matrix = Wharton's jelly; Hyaluronic acid cells are fibroblasts, white and reticular fibers present. Cells are larger, cell bodies are triangulate; cell processes appear to touch; white fibers are recognizable.
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Connective Tissue (Loose) CT3) Areolar CT (loose fibrous to fibro-elastic). Prototype of all CT; most widely distributed in the body; also the least well arranged or organized; Forms a loose gel; functions in anchoring and packing Composed of all basic CT cell types (fibroblasts, macrophages, lymphocytes) and fibers (white, yellow and reticular).
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Connective Tissue (Loose) CT4) Reticular CT - forms lattice-work stroma around lymphoid parenchyma and elsewhere. Similar to white fibers; tissue is argyrophilic. Reticular cells are similar to fibrocytes, they orient along the fibers; extremely difficult to see. Reticular cells are also similar to mesenchyme cells and are thought to be multi-potential Most common in lymphoid organs and marrow
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Connective Tissue (Dense) CT5) Dense Irregular CT (DICT) – modified (hyper-developed) areolar CT. Coarser with more and thicker fibers; forms the dermis, many capsules and sheaths Commonly referred to as "fibrous connective tissue"
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Connective Tissue (Dense) CT6) Dense Regular White CT (DRW) White fibrous or Collagenous CT; densely packed, well organized tissue Cells are fibroblasts and occur in vertical columns; they secrete white fibers around themselves. Comprises tendons, ligaments, and cornea. Commonly attach to bone or cartilage and muscle. Blood supply is poor, wounds are slow healing. Diffusion rate limits metabolism .
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Connective Tissue (Dense) Tendon DRW is well organized - hierarchy - a) primary bundle - a group of cells and fibers in an areolar CT sheath = endotendenium. b) secondary bundle - a group of primary bundles in an areolar CT sheath - peritendenium. c) Tendon - all secondary bundles in an areolar CT sheath = epitendenium. Corneal DRW is organized into layers of perpendicular fibers
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CT7) Dense Regular Yellow CT (DRY) - not as well organized as white; limited in distribution; ligamentum flava of vertebrae; suspensory ligament of penis; fibers usually occur in conjunction with white fibers. Fibers stain selectively purple with orcein,
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This note was uploaded on 01/04/2012 for the course BIO 324 taught by Professor Crawford during the Spring '09 term at Western Kentucky University.

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324Lecture7 CT - Connective Tissue Part Dos Developmental...

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