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324Lecture8 muscle - Muscle Muscle • Tissue capable of...

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Unformatted text preview: Muscle Muscle • Tissue capable of contraction and excitability.- originates from mesenchyme.- provided with well developed vascular supply and nerve network . • Tissue Types: a) skeletal, striated = voluntary. b) smooth, visceral = involuntary. c) cardiac, striated = mostly involuntary. Muscle Skeletal Muscle - forms "flesh" or "meat" of body; 40% of total body weight. – Cells form long fibers to 100 mm (4 in.); – Cells are unique - formed from a syncytium, many cells fused together for more efficient function; – Multinucleate, 35 nuclei/mm length; nuclei always at periphery of cell. – very well organized; ensheathed by areolar CT (endomysium; perimysium; epimysium). Skeletal Muscle • Cells organized into contractile units = Sarcomeres. • Sarcomeres are connected end to end = Myofibril. • Many myofibrils then make up a cell. • Sarcomere - the basic functional contractile unit; • Organization of myofilaments, thin (actin) and thick (myosin) , • ER = Sarcoplasmic Reticulum • Triads (t-tubule + 2 cisternae) at A-I Junction Skeletal Muscle...
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324Lecture8 muscle - Muscle Muscle • Tissue capable of...

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