Chapter 22 Lymphatic System and Immunity Outline

Chapter 22 Lymphatic System and Immunity Outline - CHAPTER...

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CHAPTER 22 LYMPHATIC SYSTEM AND IMMUNITY CHAPTER OVERVIEW : This chapter introduces the lymphatic system including diffuse lymphatic tissues. Inflammation, non-specific immunity and specific immunity are described and contrasted. The cells of the immune system and their functions as well as the structure and function of antibodies are discussed. OUTLINE (two to four fifty-minute lectures): Chapt. Object . Topic Outline, Chapter 22 Transparency Acetates I. Lymphatic System, p. 703 Clinical Focus, p.709 Systemic Interactions, p.733 Fig. 22.1, p.704 TA-447 1 A. Functions of the Lymphatic System 1. Fluid Balance a. Drains Excess Interstitial Fluid b. Carries Solutes and Returns them to Blood 2. Fat Absorption and the Lacteals 3. Defense a. Filtration of Foreign Materials by Spleen and Lymph Nodes b. Specialized Functions of Lymphocytes 3 B. Lymphatic Organs 1. Lymphatic Tissue Characterized by a. Lymphocytes 4 b. Macrophages c. Dendritic Cells d. Reticular Cells and Associated Reticular Fibers 2 2. Diffuse Lymphatic Tissue and Lymph Nodules Fig. 22.2, p. 704 TA-448 3. Tonsils Fig. 22.3, p.704 TA-449 b. Pharnygeal Tonsil c. Lingual Tonsil on Posterior Surface of Tongue d. Chronic Infection May Lead to Surgical Removal of Tonsils or Adenoids 2 4. Lymph Nodes Fig.22.4, p.705 TA-450 a. Size 1-25 mm Length b. Distributed Along Lymph Vessels c. Paired Aggergations d. Internal Structure
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e. Function to Filter Lymph Clinical Note, p.706 4 f. Lymphocyte Proliferation can be Stimulated - Forming Germinal Centers, esp. in Cortex 2 5. Spleen a. Size of a Clenched Fist - Located in Extreme Upper Left of Abdominal Cavity b. Internal Structure - Fibrous Capsule and Trabeculae - Blood Vessels Enter/Leave at Hilum Fig. 22.5, p.707 TA-451 c. Red Pulp - Lymphatic Tissue Associated with the Venous Sinuses and Veins d. White Pulp - Lymphatic Tissue Associated with the Arterial Supply; Periarterial Sheath e. Functions -Detects and Responds to Foreign Substances - Mechanisms Similar to Lymph Nodes f. Destroys/Removes Worn-out Red Blood Cells - Macrophages in Red Pulp g. Acts as a Blood Reservoir Clinical Note, p. 706 1). Contraction of Smooth Muscle in Splenic Blood Vessels and Capsule Move Blood Into Gen. Circulation 2 6. Thymus Gland a. Location - Superior Mediastinum, Deep to Manubrium of Sternum b. Size Varies Throughout Lifespan- Greatest Size Before Puberty Fig. 22.6, p.708 TA-452 c. Internally - Capsule with Trabeculae Forming Lobules 1). Lymphocytes in Cortex of Each Lobule d. Reticular Cells Form Blood- Thymic Barrier e. Functions to Produce Lymphocytes 1). Thymic Lymphocytes Move to Other Locations by Transport in the Blood f. Blood-Thymic Barrier Prevents Direct Response to Foreign Substances at Thymus II. Immunity, p. 707
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A. Ability to Resist Damage From Foreign Substances 1. Specificity 2. Memory B. Immunity = Ability to Destroy/Remove Pathogen Before Symptoms of Disease Develop 3 III. Innate (Nonspecific) Immunity, p. 708 A. Mechanical Barriers – Prevent Entry Into Body
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This note was uploaded on 01/04/2012 for the course BIO 324 taught by Professor Crawford during the Spring '09 term at Western Kentucky University.

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Chapter 22 Lymphatic System and Immunity Outline - CHAPTER...

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