Chapter 11 Cell Communication

Chapter 11 Cell Communication - of cell signaling Cell...

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Chapter 11 Cell Communication Lecture Outline Overview: The Cellular Internet Cell-to-cell communication is absolutely essential for multicellular organisms. Cells must communicate to coordinate their activities. Communication between cells is also important for many unicellular organisms. Biologists have discovered universal mechanisms of cellular regulation involving the  same small set of cell-signaling mechanisms. The ubiquity of these mechanisms provides additional evidence for the evolutionary  relatedness of all life. Cells most often communicate by chemical signals, although signals may take other  forms. Concept 11.1 External signals are converted into responses within the cell What messages are passed from cell to cell? How do cells respond to these messages? We will first consider communication in microbes, to gain insight into the evolution 
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Unformatted text preview: of cell signaling. Cell signaling evolved early in the history of life. One topic of cell “conversation” is sex. Saccharomyces cerevisiae, the yeast of bread, wine, and beer, identifies potential mates by chemical signaling. There are two sexes, a and α , each of which secretes a specific signaling molecule, a factor and α factor, respectively. These factors each bind to receptor proteins on the other mating type. Once the mating factors have bound to the receptors, the two cells grow toward each other and undergo other cellular changes. The two cells fuse, or mate, to form an a/ α cell containing the genes of both cells. The process by which a signal on a cell’s surface is converted into a specific cellular response is a series of steps called a signal-transduction pathway....
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