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Concept 12 - Concept 11.2 Reception A signal molecule binds...

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Concept 11.2 Reception: A signal molecule binds to a receptor protein, causing it to change shape The cell targeted by a particular chemical signal has a receptor protein on or in the target  cell that recognizes the signal molecule. Recognition occurs when the signal binds to a specific site on the receptor that is  complementary in shape to the signal. The signal molecule behaves as a  ligand,  a small molecule that binds with specificity to a  larger molecule. Ligand binding causes the receptor protein to undergo a change in shape. This may activate the receptor so that it can interact with other molecules. For other receptors, this causes aggregation of receptor molecules, leading to further  molecular events inside the cell. Most signal receptors are plasma membrane proteins, whose ligands are large water-soluble  molecules that are too large to cross the plasma membrane.
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