{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Each nucleotide that is added to a growing DNA strand comes from a nucleoside triphosphate

Each nucleotide that is added to a growing DNA strand comes from a nucleoside triphosphate

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Each nucleotide that is added to a growing DNA strand comes from a nucleoside triphosphate, a nucleoside (a nitrogenous base and a deoxyribose sugar) and a triphosphate tail. o ATP is a nucleoside triphosphate with ribose instead of deoxyribose. o Like ATP, the triphosphate monomers used for DNA synthesis are chemically reactive, partly because their triphosphate tails have an unstable cluster of negative charge. As each nucleotide is added to the growing end of a DNA strand, the last two phosphate groups are hydrolyzed to form pyrophosphate. o The exergonic hydrolysis of pyrophosphate to two inorganic phosphate molecules drives the polymerization of the nucleotide to the new strand. o The strands in the double helix are antiparallel. The sugar-phosphate backbones run in opposite directions. o Each DNA strand has a 3 end with a free hydroxyl group attached to deoxyribose and a 5 end with a free phosphate group attached to deoxyribose.
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern