Human Genetics gene disorders- mostly very rare, recessive • mutations - source of all new alleles • Tay-Sachs disease - causes lysosomes to burst o frequency of disease can vary w/ different populations and different histories o highest chance in Jewish populations • natural selection can’t always get rid of all gene disorders • Huntington disease - disorder caused by dominant gene o clinical symptoms don’t appear until middle age o those w/ disease have time to reproduce o natural selection doesn’t get rid of it • Hemophilia - inability to form blood clots; cuts won’t stop bleading • pedigree- graphical representation trait passed down many generations o uses history of the family to predict future phenotypes • sickle-cell anemia - defect in hemoglobin carrier o alters shape of red blood cells o due to change in a single amino acid o those heterozygous for this disease have more resistance to malaria • cystic fibrosis - mucus clogs lungs, liver, pancreas o
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This note was uploaded on 01/04/2012 for the course BSC BSC1005 taught by Professor Orlando,rebecca during the Fall '10 term at Broward College.