Pleiotropy - Pleiotropy Genes that affect more than one...

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Pleiotropy Genes that affect more than one trait are called pleiotropic. For example, people with Marfan syndrome may be tall, thin, have long legs, arms and fingers, and may be nearsighted. Their connective tissue is defective. If unrepaired, the connective tissue surrounding the aorta will eventually rupture and kill the person. All of these characteristics are due to a single gene. Epistasis Alleles at one locus prevent the expression of alleles at another locus. This interaction is referred to as epistasis. Example: Flower color in peas enzyme 1 enzyme 2 AA or Aa BB or Bb compound A → compound B → red pigment An individual with AA or Aa genotypes will have red flowers. AA or Aa individuals could have white flowers if the individual also has a "bb" genotype (example: AAbb). In this case, the locus for enzyme 2 prevents the expresson of the locus for enzyme 1. Genomic Imprinting
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Pleiotropy - Pleiotropy Genes that affect more than one...

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