Pyruvate Oxidation

Pyruvate Oxidation - Pyruvate Oxidation, Krebs Cycle...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Pyruvate Oxidation, Krebs Cycle pyruvate oxidation - stage 2 occurs in only in mitochondria of eukaryotes 1st forms acetyl-CoA from pyruvate, then oxidizes acetyl-CoA in Krebs cycle single "decarboxylation" reaction that cleaves off one of the carbons on pyruvate (producing acetyl group and CO2) catalyzed in mitochondria by multienzyme complex pyruvate dehydrogenase - enzyme that removes CO2 from pyruvate; has 60 subunits pyruvate + NAD+ + CoA (coenzyme A) >> acetyle-CoA + NADH + CO2 acetyl-CoA - produced by a large number of metabolic processes o key point for many catabolic processes in eukaryotes o used for fatty acid synthesis instead of Krebs cycle when ATP levels are high Krebs cycle - stage 3 9 reactions; oxidation of acetyle-CoA takes place in mitochondria matrix combines acetyle-CoA (2-carbon molecule) w/ oxaloacetate (4-carbon molecule) to extract electrons and CO2 to power proton pumps for ATP step A
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 2

Pyruvate Oxidation - Pyruvate Oxidation, Krebs Cycle...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online