Treatments for certain human conditions involve signaling pathways

Treatments for certain human conditions involve signaling pathways

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
Treatments for certain human conditions involve signaling pathways. One pathway uses cyclic GMP, or cGMP, as a signaling molecule. Its effects include the  relaxation of smooth muscle cells in artery walls. A compound was developed to treat chest pains. This compound inhibits the hydrolysis of  cGMP to GMP, prolonging the signal and increasing blood flow to the heart muscle. Under the trade name Viagra, this compound is now widely used as a treatment for erectile  dysfunction. Viagra causes dilation of blood vessels, allowing increased blood flow to  the penis. Many signal molecules in animals induce responses in their target cells via signal- transduction pathways that increase the cytosolic concentration of Ca 2+ . In animal cells, increases in Ca 2+  may cause contraction of muscle cells, secretion of certain  substances, and cell division.
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.
Ask a homework question - tutors are online