X - The incidence is in 1,500 newborn males. Most (75%)...

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X-Linked Recessive More males than females have x-linked recessive traits. A son with the trait can have parents that do not have the trait. There is no father to son transmission of the gene. The trait can skip generations; grandfather to grandson transmission can occur. If a female has the trait, her father has it, her mother is a carrier (or has it), and all her sons will have it. Color Blindness 3 different kinds 2 X-linked forms: 1 for green insensitivity (6% of all males), one for red insensitivity (2% of all males); 1 in 12 males have some form of colorblindness. Hemophilia People with hemophilia lack a clotting factor in their blood and as a result, their blood does not form clots normally. This results in excessive bleeding from even minor cuts. Internal hemorrhaging from bruises is common and leads to painful complications.
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Unformatted text preview: The incidence is in 1,500 newborn males. Most (75%) have hemophilia A, a lack of clotting factor VIII. Hemophilia B- "Christmas Disease" is a defect in clotting factor IX. Transfusions of fresh whole blood or plasma or factor concentrates control bleeding but have previously caused AIDS infections. The human gene has been isolated and cloned using recombinant DNA techniques. This is leading to improved treatment. Royal Families of Europe Victoria (granddaughter of George III) was a carrier and spread the gene to the royal families of Europe. Her granddaughter Alix- married Czar Nicholas II of Russia. The Czars son Alexis, heir to the throne, had hemophilia. The Czar's preoccupation with Alexis' health contributed to the revolution that overthrew the throne and eventually led to the communist government....
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X - The incidence is in 1,500 newborn males. Most (75%)...

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