{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Amyloid-1 - Build up of Amyloid in Alzheimer’s...

Info icon This preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Build up of Amyloid in Alzheimer’s Disease (arrow) Build Amyloid (red) in non-immunized mouse (top) is removed in mice after immunization (bottom) Removal of brain amyloid in an AD patient following active immunization (top) Persistence of brain amyloid in a nonimmunized patient (bottom) Amyloid Fibril Nerve Cell Medications may promote removal of amyloid by interfering with clumping of amyloid fibrils New medications may prevent deposits of amyloid by modulating specific enzymes modulating β -amyloid precursor protein Extracellular space TM Cytoplasm Aβ peptide COOH NH2 β -secretase Abeta-42 Selkoe DJ et al. JAMA. 2000;283:1615-1617. alpha-secretase Abeta-40 γ -secretase Abeta-42 ...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern