Genetic Disorders

Genetic Disorders - Gen et ic Disorders Inheritance of...

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Unformatted text preview: Gen et ic Disorders Inheritance of Genetic Traits Brief History First there was Gregor Mendel, a monk who studied inherited characteristics. This was followed by Francis crick and James Watson who unraveled the DNA molecule. This has led us to understanding the human genome sequence Gregor Mendel 1866 Gregor Mendel published the results of his investigations of the inheritance of "factors" in pea plants. Rosalind Franklin 1950's. Maurice Wilkins (1916- ), Rosalind Franklin (1920- 1957), Francis H. C. Crick (1916- ) of Britain and James D. Watson (1928- ) of the U.S. Discover chemical structure of DNA, starting a new branch of science--molecular biology. . Watson and Crick Watson and Crick made a model of the DNA molecule and proved that genes determine heredity Arthur Kornberg 1957 Arthur Kornberg (1918- ) of the U.S. produced DNA in a test tube. Genetic code 1966 The Genetic code was discovered; scientists are now able to predict characteristics by studying DNA. This leads to genetic engineering, genetic counseling. Barbara McClintock 1983 Barbara McClintock (1902-1992) of the U.S. was awarded the Nobel Prize for her discovery that genes are able to change position on chromosomes. DNA Fingerprinting The late 1980's. An international team of scientists began the project to map the human genome. The first crime conviction based on DNA fingerprinting, in Portland Oregon. Gene Therapy 1990. Gene therapy was used on patients for the first time. Dr. Kary Mullis 1993 Dr. Kary Mullis discovered the PCR procedure, for which he was awarded the Nobel prize . DNA Testing 1995. DNA testing in forensics cases gains fame in the O.J. Simpson trial. Cloning Begins 1997. Dolly the sheep - the first adult animal clone. Human Genome Project Imagine a world in which we will be able to treat diseases by altering our very genes giving us new ones if ours are non- functional, changing bad genes for good ones. For the first time in our existence, we are closer to understanding just what we are. We now have the tools to make the whole world better through science the science of the human genome. Genetic Disorders Mutations Gene mutations can be either inherited from a parent or acquired. A hereditary mutation is a mistake that is present in the DNA of virtually all body cells. Hereditary mutations are also called germ line mutations because the gene change exists in the reproductive cells and can be passed from generation to generation, from parent to newborn. Moreover, the mutation is copied every time body cells divide...
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Genetic Disorders - Gen et ic Disorders Inheritance of...

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