Hum_Mol_Genet_Lecture_5_February_14_2012

Hum_Mol_Genet_Lecture_5_February_14_2012 - Organization of...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon
Organization of the human genome Genome structure Nuclear vs. mitochondrial genomes Gene families Transposable elements Other repeated sequences
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
Organization of the human genome Mitochondrial genome Small (16.5 kb) circular DNA rRNA, tRNA and protein encoding genes (37) 1 gene/0.45 kb Very few repeats No introns 93% coding No recombination Maternal inheritance
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Organization of the human genome Limited autonomy of mt genomes mt encoded nuclear NADH dehydrog 7 subunits >41 subunits Succinate CoQ red 0 subunits 4 subunits Cytochrome b-c1 comp 1 subunit 10 subunits Cytochrome C oxidase 3 subunits 10 subunits ATP synthase complex 2 subunits 14 subunits tRNA components 22 tRNAs none rRNA components 2 components none Ribosomal proteins none ~80 Other mt proteins none mtDNA pol, RNA pol etc.
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Nuclear genome 3300 Mb 23 (XX) or 24 (XY) linear chromosomes 65-80,000 genes 1 gene/40kb Introns
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 8
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 01/06/2012 for the course BIOL 4753 taught by Professor Batzer,m during the Fall '08 term at LSU.

Page1 / 41

Hum_Mol_Genet_Lecture_5_February_14_2012 - Organization of...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online