Chocolate 011110 2 slide

Chocolate 011110 2 slide - Chocolate Lia M. Nightingale,...

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1 Chocolate Lia M. Nightingale, Ph.D. Typical Dark Chocolate 100g of dark chocolate contains: 32g fat = 288 kcal 59g total carbs = 236 kcal 8g fiber 5g protein = 20 kcal 544 total kcal ~1g polyphenols
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2 Chocolate Lipids Contains mainly 3 TG: P O P , P O S , S O S P = palmitic acid increases LDL O = oleic acid decreases LDL S = stearic acid no effect on LDL Overall, does not change blood lipids Chocolate Health Benefits Dec. heart disease Primary AOX Inc. HDL Thins blood Dec. blood pressure Increase eNOS & nNOS Dec. inflammation Inc. insulin sensitivity Dec. stress compounds Dec. all-cause mortality
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3 Oxygen Radical Absorbance Capacity (ORAC) Gold standard of antioxidant assays Results stated as μ mol Trolox equivalents (TE)/100 g USDA results: Dark chocolate = 21,800 Natural cocoa = 84,000 Dutched cocoa = 40,200 Orange juice = 726 Ding et al. 2006. . 3:2. ORAC = Oxygen radical absorbance capacity *Gold standard of AOX capacity.
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4 Chocolate as an AOX Flavanols donate a H to free radicals Myeloperoxidase (MPO) = enzyme that oxidizes LDL Epicatechin blocks LDL oxidation by MPO Theoretically would decrease risk of heart disease Buijsse. 2006. Arch Intern Med . 166:411. Corti et al. 2009. Circulation. 119:1433. Sies. 2005. Am J Clin Nutr . 81:304S. Cocoa has also been found to increase HDL by 24% Increased from 53 to 65 mg/dL Dose: 26g cocoa/day for 12 weeks Baba. 2007. Am J Clin Nutr . 85:709.
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5 F 2 -Isoprostane Biomarker of free-radical catalyzed arachidonic acid peroxidation in vivo Measured in serum, plasma or urine COOH OH OH HO 2 -Isoprostane High flavanol cocoa
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This note was uploaded on 01/07/2012 for the course PHCH 51311 taught by Professor Nightingale during the Summer '11 term at Palmer Chiropractic.

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Chocolate 011110 2 slide - Chocolate Lia M. Nightingale,...

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