Degenerative Disc Disease wo pics

Degenerative Disc Disease wo pics - 7/13/2010 Nucleus...

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7/13/2010 1 Lia M. Nightingale, Ph.D. Nucleus pulposus contains: Collagen (20% of dry weight) Elastin 90% water Proteoglycans(mostly aggrecan) Annulus fibrosus contains: Water Collagen (70% of dry weight) Proteoglycans(mostly aggrecan) Podichetty. 2007. Cel Mol Biol . 53:4. a. Vitamin D b. Vitamin C c. Vitamin A d. Pantothenicacid a. Repeating disaccharide chain b. Protein core surrounded by repeating disaccharide chain c. Protein core surrounded by an oligosaccharide d. None of the above Disc cell degradation exceeds synthesis Begins in teenage years Prevalence is unknown due to lack of standardized definition Has a genetic component Battie et al. 2006. J Bone Joint Surg . 88:3. Causes back pain one of the largest factors affecting the physical health status of elderly patients. Podichetty. 2007. Cel Mol Biol . 53:4.
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7/13/2010 2 Age/ Trauma ↓H 2 O in nucleus (90% → 70%) Increased compression stress ↓Blood flow ↓O 2 & nutrients
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This note was uploaded on 01/07/2012 for the course PHCH 51311 taught by Professor Nightingale during the Summer '11 term at Palmer Chiropractic.

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Degenerative Disc Disease wo pics - 7/13/2010 Nucleus...

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