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Human Para..09.08 - Intro 1 Statistics US CDC i Heart...

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Intro 1. Statistics US CDC i. Heart disease ii. Cancer iii. Stroke iv. Lower resp. disease bacterial pneumonia v. Accidents vi. Diabetes b. Underdeveloped countries - WHO i. Heart disease ii. Lower resp. disease iii. HIV/AIDS iv. Diarrheal diseases 1. Childhood death 2. Bacteria, viruses, parasites 3. Dehydration v. Tuberculosis vi. Malaria vii. Measles c. Why i. Economic problems ii. 2 billion + people travel by air each year 2. Millennium development goals (MDGs) a. UN 2000 - 2015 i. Sustainable development and eradication of poverty b. MDGs i. Eradicate extreme poverty and hunger ii. Achieve universal primary education iii. Promote gender equality and empower women iv. Reduce childhood mortality v. Improve maternal health vi. Combat HIV/AIDS, malaria and other diseases (this what we will cover in class) vii. Ensure environmental sustainability viii. Develop global partnership for development c. MDG 6 i. Most of the funds have been directed towards the poor in Africa ii. HIV/AIDS antiretroviral meds iii. Malaria drugs and bed nets d. Neglected tropical diseases (NTDs) i. STH infections (Soil Transmitted Helminth) 1. Ascariasis 4.2 bill people at risk 2. Hookworm infection 3.2 bill at risk 3. Trichuriasis 3.2 bill at risk ii. Other helminth 1. Schistosomiasis 779 mill ar risk 2. Lymphatic filariasis 1.3 bill at risk
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3. Onchoscerciasis 90 mill at risk 4. Dracunculiasis 3000 at risk iii. Protozoan 1. Leishmaniasis 350 mill at risk 2. Chagas disease 25 mill at risk 3. Human African trypanosomiasis 60 mill at risk iv. Bacterial infections 1. Trachoma blindness 2. Buruli ulcer skin 3. Leprosy skin, nervous system e. Who is at risk? i. Poverty in underdeveloped countries ii. World population = 6.8 billion people 1. About a bill live on less than $1 a day 2. About 2.7 bill live on less than $2 per day 3. NTDs a. Features i. Prevalence always with poor ii. Rural iii. Ancient diseases iv. Chronic v. Disability & disfigurement b. High disease burden but low mortality i. ~530,000 people die annually from NTDs ii. Deaths from HIV/AIDS + malaria = 2.6 million c. Disability adjusted life years (DALYs) measure health impact of NTDs by measuring effects of chronic illness time i. Number of healthy years lost from disability or premature death ii. DALY = YLL + YLD 1. YLL = average # of years of life lost 2.
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