Chapter 17 Blood- Fall 2011 posted

Chapter 17 Blood- Fall 2011 posted - EXSC224 Chapter17...

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1 Chapter 17 Blood EXSC 224
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Learning Objectives Describe components, structure, function of blood Describe the regulation of RBC formation by EPO Outline the formation and destruction of RBC’s Describe basic characteristics of anemia and polycythemia Outline the formation and destruction of a blood clot Describe the basic roles of WBC subtypes Describe the role of ABO and Rh factor blood type regarding  transfusion 2
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Blood- What does it do?? Functions Distribution Transport Gases Nutrients Waste Hormones Regulation Body Temp pH Maintenance Fluid Volume Protection Prevents blood loss infection 3 Fig 17.2
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4 Whole Blood Figure 17.1 Blood is classified as a connective tissue……. .what? Blood is a fluid (even though its classified as connective tissue) Provides no  structural support or binding of tissues The pH of blood is 7.35–7.45 Temperature is 38 ° C (100.4  ° F) Blood accounts for approximately 8% of body weight Average volume: 5–6 L for males, and 4–5 L for females Whole blood  is divided into 3 parts:  Plasma, Buffy Coat, Erythrocytes
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Plasma versus Serum Serum Everything but the  Hematocrit (Hct) or the  Red blood cells  Includes Plasma White Blood cells platelets 5 Plasma • 90% H 2 O Solutes Proteins Albumin Globulins Fibrinogen Nutrients (glucose) Electrolytes Gases Hormones
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Plasma- Functions of Solutes  Proteins Albumin- contributor to osmotic pressure Globulins- Transport Fibrinogen- aid in clotting of blood Nutrients Glucose, amino acids, fatty acids, etc… Electrolytes (Na + , K + , Ca +2 , Cl - ) – Gases- O 2 , CO 2 Hormones…. .you know all about them by now 6
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7 Formed Elements: Erythrocytes =            Red blood cells  (RBCs) = Hemtocrit Figure 17.3 Biconcave discs no nucleus (important!) essentially no organelles Filled with  hemoglobin (Hb)  97%  Spectrin   plasma membrane protein  give erythrocytes their flexibility Allow them to change shape as 
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Chapter 17 Blood- Fall 2011 posted - EXSC224 Chapter17...

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