HyperparathyroidismAndHypercalcemia-1

HyperparathyroidismAndHypercalcemia-1 - Hyperparathyroidism...

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Hyperparathyroidism and Hypercalcemia Julie E. Park April 5, 2005 Tuesday Conference
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Anatomy 4 glands (2-6) 1 x 3 x 5 mm 30-50 mg
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Anatomy Superior Post or lateral to upper thyroid pole Sup or inf thyroid a. Post to RLN Inferior Inf, post, or immediately lat lower thyroid pole Inf thyroid a. Ant to RLN
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Embryology Branchial pouches 3 inferior parathyroid and thymus 4 superior parathyroid and thyroid
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Ectopic locations parathyroid Thymus Thyrothymic ligament Tracheoesophageal groove Retroesophageal space Carotid sheath Intrathyroid
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Diagnosis Hypercalcemia Elevated PTH
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Parathyroid hormone Regulates serum calcium 84 amino acid polypeptide N-terminal frag – biologically active C- terminal frag – inactive Intact PTH half-life 2 to 5 minutes
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Differential Diagnosis HPT Malignancy Vit A or Vit D intoxication Thiazide diurectics Hyperthyroidism Milk-alkali syndrone
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HyperparathyroidismAndHypercalcemia-1 - Hyperparathyroidism...

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