Bio1_09_Metabolism - 1 2 3 1 2 4 1 2 5 1 2 6 7 1 2 8 1 9 1...

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1 Overview – Flow of energy – Metabolic reactions – Enzymes Flow of Energy What is Energy? • Potential energy – Chemical energy • Kinetic energy – Mechanical energy What is Energy? • 1 st law of thermodynamics – Conservation of energy – Energy cannot be created or destroyed – Can change form • 2 nd law of thermodynamics – Direction of energy – Energy cannot change forms without loss of usable energy – Entropy •Increase of disorder What is Metabolism? • Metabolism – Sum of all chemical reactions in a cell – E.g., A + B b C + D – Free energy •(Energy of reactants) – (energy of products) •Spontaneous if negative Energy in Cells • Cells use energy for: – Chemical work – Mechanical work – Electrochemical work • Decrease in usable energy • Where do our cells get energy from? Reactions in Cells • Exergonic reactions – Release energy • Endergonic reactions – Require energy input • ATP – Energy currency – Energy transfer • ATP b ADP + P i releases energy – Why do cells need energy? • ADP + P b ATP requires energy – Most ATP is built by chemiosmosis Coupled Reactions • Exergonic reaction coupled with endergonic reaction – E.g., ATP breakdown coupled to energy-requiring reaction 1 2 3 1 2 4 1 2 5 1 2 6 7 1 2 8 1 9 1
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Bio1_09_Metabolism - 1 2 3 1 2 4 1 2 5 1 2 6 7 1 2 8 1 9 1...

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