Bio1_13_Mitosis - 1 2 3 4 5 6 7 1 2 8 1 2 9 1 2 10 Overview...

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1 Overview: Cell Division • Ch. 9: Cell Division – Cell cycle – Mitosis – Cancer – Prokaryotic cell division The Cell Cycle: Interphase • G 1 stage: growth • S stage: DNA replication • G 2 stage: preparation for division Assignment 1 • Think, Pair, Share • Topic: Many cells (such as brain cells) go into a stage when they no longer divide. – What are those cells doing if they are not dividing? – Why do skin cells divide frequently when other types of cells do not? The Cell Cycle: Mitosis • M stage – Prophase – Metaphase – Anaphase – Telophase Assignment 2 • Think, Pair, Share • What are the four stages of the cell cycle? – During which of these stages is the DNA replicated? – When does cell division occur? Control of the Cell Cycle • Growth factors – Signaling proteins – Stimulate cell to complete cell cycle • Cell cycle checkpoints – Determine if cycle continues – Damage leads to apoptosis •Programmed cell death •Caused by caspases (enzymes) Cell Cycle Checkpoints • G 1 checkpoint • G 2 checkpoint • M checkpoint The G 1 Checkpoint • Evaluates growth signals – CDK adds P to RB – E2F released – Activates genes that complete cell cycle • Determines nutrient availability – G 0 : P removed from RB if nutrients low – G 1 : P added to RB if nutrients available The G 1 Checkpoint • Assesses DNA integrity – CDK adds
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This note was uploaded on 01/12/2012 for the course BIOLOGY 1 taught by Professor Teresafinnern during the Fall '11 term at Riverside Community College.

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Bio1_13_Mitosis - 1 2 3 4 5 6 7 1 2 8 1 2 9 1 2 10 Overview...

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