Renal Physiology - RENAL PHYSIOLOGY BMED 3100 Functions of...

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BMED 3100 RENAL PHYSIOLOGY
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BMED 3100 Functions of the Kidneys Regulation of extracellular fluid volume integrates with the cardiovascular system to maintain BP and tissue perfusion within acceptable ranges Regulation of osmolarity thirst behavioral drive maintains ~290 mOsM Maintenance of ion balance Na + , K + , and Ca 2+ Homeostatic regulation of pH Kidneys remove H + and conserve HCO 3 - if too acidic Excretion of wastes and foreign substances by products of metabolism – creatine, urea, uric acid foreign substances - saccharin Production of hormones not an endocrine gland, but synthesizes erythropoietin releases renin (enzyme in Na balance)
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BMED 3100 Anatomy: Urinary System Ureter : hollow tubes leaving each kidney, takes modified fluid to the bladder Bladder : fills with urine Urethra : single tube used for urine excretion Renal arteries : branch off abdominal aorta, supply blood to kidneys Renal veins : carry blood from kidneys back to inferior vena cava Kidneys receive 20-25% of CO
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BMED 3100 Anatomy: Structure of the Kidney Kidney Cortex : outer layer Medulla : inner layer Nephrons : microscopic tubules and form the organization layers nephron is the functional unit of the kidney approx. 1 million nephrons/ kidney 80% of nephrons are almost completely in cortex some nephrons dip into medulla
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Afferent arteriole : carries blood arriving to nephron Glomerulus : ball- shaped mass, site where plasma filters out of the capillaries into the lumen of the tubule efferent arteriole : blood leaving the glomerulus, then enters peritubular capillaries
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This note was uploaded on 01/12/2012 for the course BMED 3110 taught by Professor Staff during the Spring '08 term at Georgia Institute of Technology.

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Renal Physiology - RENAL PHYSIOLOGY BMED 3100 Functions of...

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