Tissues - (desmosomes tight junctions gap junctions BMED...

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BMED 3100 Tissues External environmental influences Systemic milieu Tissue Niche Stem cell Humoral Paracrine Structural Physical Metabolic Neural Local influences on stem cell function Adapted from Scadden, Nature 44: 1075, The Stem Cell Niche
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BMED 3100 Germ Layers Endoderm – innermost, gut, lungs, liver Mesoderm – middle, connective tissue, muscle, vascular system Ectoderm – outermost, CNS, PNS, epidermis Tissues
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BMED 3100 Tissue Specialization Determination: commitment to a certain fate Determination precedes differentiation Mosaic determination : developmental determinants placed into cells early in development Regulative determination : determination occurs by cell-cell signals Differentiation: the mechanism by which that fate is achieved Soluble factors (chemical communication) Substrate (physical communication) Pattern formation (cell memory) Cell junctions
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Unformatted text preview: (desmosomes, tight junctions, gap junctions) BMED 3100 Tissue Types: 1. Muscular – skeletal ( movement, maintenance of posture ); smooth ( voluntary and involuntary contractions ); heart ( involuntary pumping of heart ) 2. Nervous – central and peripheral nervous tissue ( communication, regulation) 3. Epithelial – lining ( protection, absorption, secretion ) 4. Connective – connective tissue proper (fat, tendon), dense (cartilage and bone), loose ( support, defense, repair, transport, structure ) BMED 3100 Muscle Tissue Muscle tissue is excitable Three types of muscle: • Skeletal • Smooth • Cardiac BMED 3100 Nervous Tissue Nervous tissue is excitable BMED 3100 Epithelial Tissue BMED 3100 Epithelial Tissue BMED 3100 Connective Tissue BMED 3100 Connective Tissue BMED 3100 e.g., Loose Connective Tissue BMED 3100 Tissues Organ Systems...
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This note was uploaded on 01/12/2012 for the course BMED 3110 taught by Professor Staff during the Spring '08 term at Georgia Tech.

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Tissues - (desmosomes tight junctions gap junctions BMED...

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