Eightlec - Genetic Defects of Dogs ANS 3384 Hip Dysplasia Characteristics Shallow/malformed acetabulum Information http/www.offa.org

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Genetic Defects of Dogs ANS 3384
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Hip Dysplasia • Characteristics: – Shallow/malformed acetabulum • Information: http://www.offa.org/ http://www.workingdogs.com/doc0090.htm • Causes: – Genetic predisposition– h 2 = ~.30 – Excessive early growth
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Control of Hip Dysplasia • Have all breeding animals evaluated for hip dysplasia – OFA or PennHip • Attempt to use as parents only animals with 2 or more generations of ancestors free of detectable hip dysplasia • If possible determine the status of siblings or parents, grandparents, etc.
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Collie Eye Anomaly • inadequate development of the choroid, a thin layer of blood vessels that delivers oxygen and nutrients to the retina (called hypoplasia of the choroid or chorioretinal dysplasia) • coloboma - a cleft or defect of the optic disc or adjacent areas • staphyloma - an area of thinning in the sclera which is adjacent to the choroid
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Collie Eye Anomaly • retinal detachment with or without hemorrhage - a complication associated with the other defects. – This is the worst case scenario, if it is present in both eyes, the puppy is blind • At least 80% of Collies are affected by CEA, a recessive condition • Only rarely are homozygous normal individuals found
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Collie Eye Anomaly • Because most affected collies can perform all normal duties/functions and are acceptable to the buying public, there has been no real push to remove this syndrome from the breed. • The most common form of CEA is choroidal hypoplasia (CH). • CH does not become worse nor does it progress to any other type of CEA
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Other Breeds with CEA Border Collies Australian Shepherds Shetland Sheepdogs
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Von Willebrand's Disease • Von Willebrand’s disease (wVD) is the most common inherited bleeding disorder in dogs. • Dobermans, Pembroke Welsh Corgis,
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This note was uploaded on 01/15/2012 for the course ANS 3384 taught by Professor Olson during the Spring '09 term at University of Florida.

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Eightlec - Genetic Defects of Dogs ANS 3384 Hip Dysplasia Characteristics Shallow/malformed acetabulum Information http/www.offa.org

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