Chapter 25

Chapter 25 - Microbial Diseases of the Digestive System...

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Unformatted text preview: Microbial Diseases of the Digestive System Chapter 25 Normal Microbial Flora of the Digestive System • Mouth • 1 ml saliva = millions of bacteria • Stomach and small intestine • Few organisms due to HCl and rapid movement of food • Large intestine • 100 billion bacteria per gram of feces • 40 % of fecal mass is microbial cell material • Lactobacillus, Bacteriodes, Enterobacter, E. coli. Proteus spp. Bacterial Diseases of Lower G.I. • Infections • Pathogens enters G.I. Tract and multiples • Bacteria may penetrate the intestinal mucosa or may pass to other systemic organs • Delay in appearance of symptoms while pathogen increases in number or invades tissue • Usually a fever • Intoxications • Ingestion of a preformed toxin • Sudden onset of symptoms ( few hours ) • Fever not always present Bacterial Diseases of Lower G.I. • Diarrhea – infections and intoxications • Blood or mucus - dysentery • Abdominal cramps, nausea and vomiting • Defense mechanism to rid body of harmful material • Gastroenteritis • Inflammation of stomach or intestinal mucosa Campylobacter Gastroenteritis • Campylobacter jejuni • Gram (-), microaerophilic spiral • Most common cause of food borne illness in the U.S. • Found in the intestines of many animals, especially poultry • Almost all retail chicken is contaminated • 60 % of cattle is contaminated • 2 million cases per year Escherichia Gastroenteritis • 1. ETEC - e nterot oxigenic E . c oli • Not invasive • Enterotoxin – watery diarrhea • 2. EIEC - e nteroi nvasive E . c oli • Invades intestinal wall • Inflammation, fever & Shigella-like dysentery • 3. EHEC - 3....
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This note was uploaded on 01/13/2012 for the course MMBIO 361 taught by Professor Bernard during the Fall '11 term at BYU.

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Chapter 25 - Microbial Diseases of the Digestive System...

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