The Immune System lecture I - The Immune System The immune...

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The immune system protects us from infection and provides resistance to disease There are 2 arms of the immune system The Innate system – always prepared non-specific made of barriers, physical and chemical chemical signals / inflamation The adaptive system -- The immune response Part 1 – Innate defenses 1. Surface barriers a. Skin and mucous membranes i. Provide physical obstacles to foreign pathogens ii. Produce a variety of chemicals 1. acidic skin secretions 2. HCl in stomach 3. saliva (lysozyme) 4. Lacrimal fluid “ 5. mucous However the external barriers can be breeched and internal defences take over 2. Internal defenses – cells and chemicals a. Phagocytes – chiefly macrophages and monocytes, neutrophils, eosinophils, mast cells Methods of phagocytosis (fig 22.1) b. NK cells – large granular lymphocytes – kill indiscriminately, not phagocytic, but attack membranes with perforins. Also secrete chemicals to enhance inflammation. c. Inflammation – tissue response to injury.
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The Immune System lecture I - The Immune System The immune...

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