The Immune System lecture II - The Immune System Part 2...

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Part 2 – Adaptive Defences - Antigen specific - Systemic - Have memory There are 2 types of adaptive immunity 1. Humoral – antibody mediated, antibodies in body fluids 2. Cellular or cell mediated immunity a. Antigens (non-self molecules) mobilize the immune system Complete antigen and haptens - Complete antigens – molecules that stimulate proliferation of specific lymphocytes and antibody production “immunogenicity”, and react with products of Immunogenicity “reactivity” - Haptens need to be bound to protein carriers in order to have immunogenicity and reactivity - Antigenic determinants – the specific part of an entire antigen that is immunogenic (fig 22.6). Most naturally occuring antigens have a variety of antigenic determinants - Self-antigens – MHC (major histocompatability complexes) proteins. All cells have surface markers. Including our own. These self-antigens are not immunogenic to us, but they are to other people. Markers that indicate self are called MHC. - Identical twins are the only people with identical MHC markers. -
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This note was uploaded on 01/16/2012 for the course BIOLOGY 251 taught by Professor Lancebowen during the Fall '10 term at Truckee Meadows Community College.

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The Immune System lecture II - The Immune System Part 2...

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