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Unformatted text preview: N-asparagine X- any S-serine T- if protein contain this sequence it doesnt necessarily mean that it will get modified . ... sometimes it folds. Another example of modification :- addition of a phosphate group. -consensus sequence recognized by protein kinase A, an enzyme that phosphorylates serine or threonine residues is RRXSZ or RRXTZ where X is a small amino acid and Z is a large hydrophobic residue. Proteolytic modifications- many proteins have been found to be trimmed or have pieces cleaved from them by specific proteolytic enzymes. -this was found early in the case of some enzymes in the digestive system that are stored in the pancreas as inactive precursors, called zymogens and activated by proteases cleavage after release into the small intestine....
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- Fall '08