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Unformatted text preview: 1- specificity of enzyme 2. the physical and chemical architechture of the active site. 3. the kinetic mechanism of reaction there are 3 classical types of inhibition 1. competitive 2. noncompetitive 3. uncompetitive Competitive inhibition-inhibitor only binds to the free enzyme and competes with the substrate for the active site. or binds close to the site and prevents substrate from binding.-competitive very closely resembles the substrate Ks-- dissociation constant for the enzyme substrate complex. . The Vmax is not affected but Ks is affected in the machaelis -menten equation....
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- Fall '08