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Unformatted text preview: substrate is required to attain a given reaction rate. The organism needs a balance of purines and pyrimidines ATP - acts as a positive effector of ATCase and helps cell maintain a balance of CTP and ATP Allosteric regulation of enzymes is noncovalent regulation of enzymes Covalent regulation of enzymes-covalent addition or removal of a molecule to an enzyme can also modify its activity. most of these modifications are reversible ex: phosphorylation and dephosphorylation enymes catalyzing phosphorylation reactions are called protein kinases -- can enable the regulation of an enzyme to be fine tuned according to a specific substrate, tissue or time of development. Protein kinase A recognizes the following consensus sequences: RRXSZ or RRXTZ S or T is the site of phosphorylation X is a small residue (either glycine or alanine) Z is an amino acid with large hydrophobic R group ( trp or phe)...
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- Fall '08
- Enzyme, Adenosine triphosphate, regulatory subunits, enzyme activity. binds